Mindfulness-based intervention as a symptom management strategy in patients with end-stage renal disease: A controlled clinical trial.

Abstract

The study's purpose was to examine the effect of mindfulness-based intervention (MBI) on physical and psychological symptoms in patients with end-stage renal disease (ESRD) in Jordan. A repeated-measure randomized control study was conducted in a haemodialysis unit in Jordan between April 2023 and July 2023. Participants (N= 61) were selected using convenience sampling and then randomly assigned into experimental and control groups. The experimental group performed 30-min MBI, three times a week for 8weeks during haemodialysis sessions. The Depression, Anxiety and Stress Scale-21 and the Patient Health Questionnaire-15 were used to measure the outcomes at baseline, after 5weeks of the intervention and at the end of the intervention. Mixed-model repeated-measure ANOVAs revealed that the experimental group showed significantly lower levels of stress, depression and physical symptoms than the control group over time. Within-subject repeated-measure ANOVAs revealed that, in the experimental group, physical symptoms improve significantly over the three points of time. However, significant reductions in psychological symptoms occurred 5weeks after initiating the intervention, but there was no further significant improvement at the end of the intervention. The study supports the integration of MBI as a symptom management strategy into nursing care plans of patients with ESRD. Clinical trial.gov; registration ID: NCT06064708.