Mind-Body Exercise (Wuqinxi) for Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Ke Wang,Zhaowei Kong,Jing Liu,Yanjie Zhang,Shijie Liu

doi:10.3390/ijerph16010072

Abstract

Objective: This study is the first meta-analysis investigating the rehabilitative effects of Wuqinxi for patients with chronic obstructive pulmonary disease (COPD). Methods: Five electronic databases (PubMed, Web of Science, Scopus, CNKI, and Wanfang) from inception until early November 2018 were searched. All randomized controlled trials (RCT) using Wuqinxi as the main intervention component were included for meta-analysis. The pooled effect sizes (Standardized mean difference, SMD) were calculated to determine the magnitude of the Wuqinxi intervention effect. Moderator analysis was only conducted for total training time. Results: Overall results of the meta-analysis indicated that Wuqinxi exercise significantly improved exercise capability (SMD = 1.18, 95% CI 0.53 to 1.84, e < 0.001, I2 = 84.97%), FEV1 (SMD = 0.44, 95% CI 0.12 to 0.77, e < 0.001, I2 = 33.77%), FEV1% (SMD = 0.59, 95% CI 0.24 to 0.93, e < 0.001, I2 = 63.79%), FEV1/FVC (SMD = 0.65, 95% CI 0.37 to 0.93, e = 0.006, I2 = 44.32%) and CCQ (SMD = 1.23, 95% CI 0.31 to 2.14, e = 0.01, I2 = 93.32%). Conclusions: With no occurrence of adverse event, clinicians could try to incorporate Wuqinxi exercise into their first-line rehabilitation regime for COPD patients.

Highlights

Environmental problems, especially air pollution, are affecting respiratory health on a global scale [1]
The included studies met the criteria if they: (1) were published in a peer-reviewed journal (2) were a randomized controlled trial, randomized controlled trials (RCT); (3) recruited human subjects diagnosed with chronic obstructive pulmonary disease (COPD); (4) used Wuqinxi as the main intervention component, while the control condition involved other treatment or no intervention; (5) reported at least one health-associated outcome
The remaining of 21 potentially relevant articles were further assessed against the inclusion criteria, and 13 were excluded

Summary

Introduction

Environmental problems, especially air pollution, are affecting respiratory health on a global scale [1]. Chronic obstructive pulmonary disease (COPD) is among the leading kinds of chronic respiratory diseases that are among the leading causes of mortality and morbidity all over the world [2]. COPD is characterized by progressive, incurable airflow limitation, and is commonly caused by exposure to noxious particles or gases that result in airway or alveolar abnormalities [3]. Patients with COPD have a significant number of coexisting problems such as physical inactivity, psychological issues (anxiety and depression), cardiovascular disease and lung cancer [4]. Burden of Disease study reported that the prevalence of COPD increased by about 45% compared to. Res. Public Health 2019, 16, 72; doi:10.3390/ijerph16010072 www.mdpi.com/journal/ijerph

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Conclusion