Abstract
In January 2009, the FDA approved milnacipran (Savella), a selective serotonin and norepinephrine reuptake inhibitor, for treatment of fibromyalgia. In an industry-sponsored randomized trial, 1025 U.S. and Canadian patients with fibromyalgia (mean duration of symptoms, 11 years) received milnacipran or placebo. Dosing started at 12.5 mg once daily and was titrated to …
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