Abstract
Therefore, the development of a mild and efficient method for the synthesis of amide bonds in the absence of a base is strongly desired. In this communication, we report on a new and efficient method for the synthesis of amides from corres-ponding acyl chlorides and amines using a catalytic amount of cooper (II) oxide (CuO). To the best of our knowledge, this is the first demonstration of CuO-catalyzed acylation of amines and alcohols.Initially, we chose benzoyl chloride and cyclohexylamine as model compounds. When benzoyl chloride was treated with cyclohexylamine (1 equiv) and CuO (1 equiv) in CH
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
