Abstract

During the past decade, a number of European investigators have been interested in studying the parotid glands. Many clinical observations have been made, and considerable experimental work has been done in an effort to learn the true function and significance of the salivary glands. In spite of the tremendous amount of work that has been done on this problem, the question as to whether or not the salivary glands have an internal secretion has not yet been answered satisfactorily. Considerable clinical and experimental evidence has accrued to indicate that there probably is an indirect if not a direct relationship between the salivary glands and the glands of internal secretion. That the parotid glands have a function in some way analogous or related to that of the pancreas has been suggested by recent clinical observations and experiments. Swelling of the parotid glands, or Mikulicz's disease, has been observed recently in a

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