Abstract

Researchers at Chung Shan Medical University, Taichung, and other centers in Taiwan analyzed 969 EEGs from 463 children with epilepsy to determine outcome differences over 3 years between those with fixed epileptic foci and those with migrated foci.

Highlights

  • Researchers at Chung Shan Medical University, Taichung, and other centers in Taiwan analyzed 969 EEGs from 463 children with epilepsy to determine outcome differences over 3 years between those with fixed epileptic foci and those with migrated foci

  • Acute gastroenteritis was associated with nonfebrile-illness seizures more frequently than febrile seizures (47% cf 28%, respectively, P=0.05)

  • Children with acute gastroenteritis experienced multiple seizures within the first 24 hours significantly more often than children with febrile seizures (58% and 27%, respectively, p=0.001)

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Summary

OUTCOME OF FIRST SEIZURE FOLLOWING ACUTE ILLNESS

Researchers at Seattle Children's Research Institute and University of Washington report a prospective longitudinal study of children who presented with a first-time seizure associated with a viral infectious illness. Acute gastroenteritis was associated with nonfebrile-illness seizures more frequently than febrile seizures (47% cf 28%, respectively, P=0.05). Children with acute gastroenteritis at first seizure, regardless of fever, had fewer seizure recurrences compared with children with other acute illnesses. Nonfebrile illness seizures are regarded as a distinct category of provoked seizures associated with a viral infection, frequently acute gastrointestinal. The acute gastrointestinal illness nonfebrile seizure has a lower rate of seizure recurrence and few neurologic complications. Fever was absent in the 24 hours before or 2 hours after the first seizure in 58% of children with gastrointestinal illness-associated seizures in the above study

MIGRATION OF EEG SPIKE FOCI AND EPILEPSY OUTCOME
Findings
INFECTIOUS DISORDERS
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