Abstract
Migrations cause the gene flow in populations and represent the factor that changes its genetic structure. At the end of the previous century there was a significant migration and mixing of distant populations in the area of Republic of Srpska. Such changes inevitably cause the change of gene frequencies. The aim of our research is to analyze the distribution of phenotipic characteristics and to determine allele frequency for AB0 and Rh blood types in the mentioned area, and to compare the results with the previous research. The results were obtained from the Institute of Transfusion Medicine for the regions of Banja Luka, Prijedor, Gradiška, Novi Grad, Doboj and Trebinje. The results, displayed as tables and graphs, were analyzed by standard statistical methods, and they imply certain changes in allele frequencies that are not statistically significant.
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