Abstract

Migraine which is a mode of a headache affects all age groups and both genders with big varieties. It is treated symptomatically and plaintively in the most majority of the standard treatment all over the world. According to my work on the biological bases of the surgical pathologies for the last twenty years I noticed and analyzed the possibly of migraine could be a complication to the chronic inflammation of the skull base Para-nasal air sinuses. The modalities of migraine are related to the involved air sinus/es and to the nature of its/their affection. Chronic sinusitis in turn is a complication to a known chronic active intracellular bacterial systemic infection. This vision is gone with the trial treatment for that last twenty years all put on strict clinical analysis and clinical trial treatment directed to the systemic infection in question which is a chronic brucellosis in my career. Recently PCR open tissue biopsy admitted in to the work up of the patient which supported this view to average of 40% in a face of nearly a hundred percent successful trial treatment without any modality of palliative treatment, this involved hundred of patients with the widest range of migraine affection.

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