Abstract
BackgroundMigraine, tension type headache (TTH), and hypothyroidism are clinical problems that affect patient daily activities and quality of life.ObjectivesThe purpose of this study was to investigate the potential association between hypothyroidism in patients with migraine and TTH.Patients and methodsTwo hundred and twelve patients with migraine and TTH and one hundred control subjects underwent clinical evaluation, assessment of thyroid hormones, and thyroid ultrasound.ResultsSubclinical and overt hypothyroidism were significantly higher in patients with migraine and TTH (P = 0.001) than control subjects. Patients with migraine and TTH showed significantly more abnormal thyroid gland morphology than healthy control (P = 0.027). Hypothyroidism is significantly expressed in chronic TTH more than TTH with infrequent or frequent TTH (P = 0.009).ConclusionsPatients having migraine and TTH more prone to develop hypothyroidism when compared with control group. Also patients with chronic TTH are susceptible to develop hypothyroidism (either subclinical or overt) when compared with patients having frequent or infrequent TTH.
Highlights
Migraine and tension type headache (TTH) disorders are among the top six most prevalent disorders and the third cause of disability worldwide in individuals under the age of 50 with a major impact on activities of daily living and quality of life [1, 2].Tension-type headache (TTH) is defined as a mild to moderate band-like pressure headache associated with some somatic and emotional symptoms
Subjects In a cross-sectional study, we investigated two hundred and twelve patients with migraine and tension type headache and one hundred, age- and sex-matched healthy control subjects
Binary logistic regression (BLR) analysis was run to assess the influence of having migraine or TTH versus no headache on the likelihood that participants will exhibit hypothyroidism
Summary
Migraine and tension type headache (TTH) disorders are among the top six most prevalent disorders and the third cause of disability worldwide in individuals under the age of 50 with a major impact on activities of daily living and quality of life [1, 2].Tension-type headache (TTH) is defined as a mild to moderate band-like pressure headache associated with some somatic and emotional symptoms. Typical characteristics of migraine headache are unilateral location, pulsating quality, moderate or severe intensity, aggravation by routine physical activity, and Hypothyroidism prevalence in general population in Europe ranged between 0.2 and 5.3% and usually this represents thyroid hormone deficiency. It affects women more than men and is more common in older age (≥ 65 years) with clinical burden related to major organs including neurological symptoms [5]. Tension type headache (TTH), and hypothyroidism are clinical problems that affect patient daily activities and quality of life
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