Abstract

Headaches and sleep problems are burdensome in daily life. They can co-occur and aggravate each other. The prevalence of sleep disorders is high in chronic headache and migraine patients, suggesting a close clinical relationship between these conditions. Structures from the brainstem to the cerebral cortex are related to sleep and headache modulation. In addition, various neurochemicals are related to and overlapped in the modulation of sleep and headache. In this paper, we briefly review the association between migraine and sleep disorders, including insomnia, sleep-related breathing disorders, central disorders of hypersomnolence, circadian rhythm sleep-wake disorder, parasomnias, and sleep-related movement disorders. Keywords: Sleep, Sleep disorders, Insomnia, Obstructive sleep apnea, Migraine, Restless legs syndrome

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