Abstract
Reviewed was the clinical course of 76 patients with a history of previous cesarean section from among 1,626 patients undergoing midtrimester abortion induced with intra-amniotic hyperosmolar urea and prostaglandin F2α. The cesarean section group had long injection-abortion intervals, more frequently received additional oxytocin for augmentation, and more frequently experienced incomplete abortion. Also, one patient experienced a uterine rupture. A review of the literature dealing with uterine rupture subsequent to induced midtrimester abortion revealed that the typical patient was older and multiparous, had an injection-abortion interval of more than 24 hours, and had received intravenous oxytocin continuously for more than 12 hours. Although there has been no previous report of a uterine rupture with midtrimester abortion in patients who have undergone a prior cesarean section, because of the present findings, such patients require careful monitoring and the judicious use of oxytocic agents.
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