Abstract
In Saudi Arabia, including regions of Riyadh and Al Ahsa, pseudoparticle neutralisation (ppNT) and microneutralisation (MNT) tests detected no antibodies to Middle East Respiratory Syndrome coronavirus (MERS-CoV) in sheep (n= 100), goats (n= 45), cattle (n= 50) and chickens (n= 240). Dromedary camels however, had a high prevalence of MERS-CoV antibodies. Bovine coronavirus (BCoV) infected sera from cattle had no cross-reactivity in MERS-CoV ppNT or MNT, while many dromedary camels’ sera reacted to both BCoV and MERS-CoV. Some nevertheless displayed specific serologic reaction profiles to MERS-CoV.
Highlights
Article submitted on 04 December 2013 / published on 12 December 2013 In Saudi Arabia, including regions of Riyadh and Al Ahsa, pseudoparticle neutralisation and microneutralisation (MNT) tests detected no antibodies to Middle East Respiratory Syndrome coronavirus (MERS-CoV) in sheep (n= 100), goats (n= 45), cattle (n= 50) and chickens (n= 240)
In a seroepidemiological study of domestic livestock and dromedary camels from Saudi Arabia, we find that only dromedary camels have evidence of seropositivity to Middle East Respiratory Syndrome coronavirus (MERS-CoV), suggesting an infection with a MERS-CoV-like virus
Dromedary camels from the central province of Riyadh as well as the eastern province, Al Ahsa, had comparably high levels of seropositivity to MERS-CoV by pseudoparticle neutralisation (ppNT) tests
Summary
Article submitted on 04 December 2013 / published on 12 December 2013 In Saudi Arabia, including regions of Riyadh and Al Ahsa, pseudoparticle neutralisation (ppNT) and microneutralisation (MNT) tests detected no antibodies to Middle East Respiratory Syndrome coronavirus (MERS-CoV) in sheep (n= 100), goats (n= 45), cattle (n= 50) and chickens (n= 240). Bovine coronavirus (BCoV) infected sera from cattle had no cross-reactivity in MERS-CoV ppNT or MNT, while many dromedary camels’ sera reacted to both BCoV and MERS-CoV.
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