Abstract
Nine cases among 1000 adults referred to our EEG Laboratory were found to have epileptiform discharges at the C-Z area, predominantly in the awake state. These were in the form of isolated spike and wave complexes in five cases (0.5%), and Mu-like rhythms in four (0.4%). In all cases, variable degrees of dementia were found, and the CT scan of the head revealed mild to moderate cerebral atrophy and ventricular enlargement, confirmed by quantitative measurement. It is postulated that diffuse cortical and subcortical structural alteration is a factor responsible for the genesis of mid-line epileptiform activity in adult EEG's.
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