Abstract
A new series of highly functionalized 1,5‐benzodiazepine derivatives 5a–x have been synthesized from 3‐[(1E)‐N‐(2‐aminophenyl) ethanimidoyl]‐4‐hydroxyl‐2H‐chromen‐2‐one 3a–c and pyrazole aldehyde 4a–h using catalytic amount of triflouro acetic acid under microwave irradiation. The main significant of the present procedure is shorter reaction time, easy work up procedure, and excellent yield with high purity. The structures of all the compounds were established on the basis of their IR, NMR, and mass spectral data and have been screened for their antimicrobial activity and antifungal activity.
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