Abstract
Microwave energy radiation is widely used as a method for rapidly sacrificing small laboratory animals so that measurements of endogenous levels of labile neurochemical substances can be assessed after various drug treatments or pharmacological maneuvers. Several factors are important to insure that microwave energy is efficiently coupled to the rodent brain, including: the frequency of microwave radiation, the size of the waveguide for the propagation of the energy, the tuning of the waveguide system, the placement of the animal at the point of maximum power within the waveguide, the amount of power which is delivered, the time during which the power is delivered, and whether the animal is restrained during the microwave protocol.
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