Abstract

A series of new pyrazole-based 1,2,3-triazole derivatives were synthesized through the microwave-assisted Huisgen click reaction from 1-phenyl-3-[3-(prop-2-yn-1-yloxy)phenyl]-1H-pyrazole-4-carbaldehyde and organic azides with the use of redox system CuSO4·5H2O–sodium ascorbate. The method provided short reaction times and isolation of 1,4-disubstituted 1,2,3-triazoles in high yield. All the prepared compounds were evaluated for antimicrobial activity and the most of them displayed promising results.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.