Abstract

A new series of 4,4'-(3,5-diphenethylbenzo[1,2-b:5,4-b']difuran-2,6-diyl)bis(N-(het)arylthiazol-2-amine) derivatives have been synthesized from 1,1'-(3,5-diphenethylbenzo[1,2-b:5,4-b']difuran-2,6-diyl)diethanone O,O'-diacetyl dioxime and substituted isothiocyanates under conventional and microwave irradiation conditions. The obtained products were subjected to in vitro antibacterial and antimycobacterial activity tests. Some of the compounds exhibited noteworthy antibacterial activity against Bacillus subtilis (+ve) and Pseudomonas aeruginosa (-ve) strains and antimycobacterial activity against Mycobacterium bovis strain.

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