Microwave-assisted synthesis of nitrogen-containing heterocycles

Abstract

In the recent years, microwave (MW) radiation is widely used as a source of heating in organic synthesis. Since the discovery of the MW heating approach, MW-assisted reaction has emerged as a new green-method in organic synthesis as it provides spectacular accelerations, higher yields under milder reaction conditions, and higher product purities, and it reduces pollution of the environment through the use of solvent-free reaction protocols. N-containing heterocycles hold a special place among pharmaceutically significant natural products and synthetic compounds needed for any developed human society. Therefore, organic chemists have been engaged in extensive efforts to produce these compounds following various greener techniques, primarily to circumvent growing environmental concerns. In this review, we discuss only the MW-assisted synthesis of N-containing heterocyclic compounds.