Abstract
We reported here the microwave-assisted synthesis of 3,5-disubstituted 1,2,4-triazole based piperazine amide and urea derivatives with very good yield under mild reaction conditions.
Highlights
Substituted 1,2,4-triazole and its derivatives have gained a considerable interest of the medicinal chemist in search for the new drugs
We reported here the microwave assisted synthesis of 3,5-disubstituted 1,2,4-triazole based piperazine amide and urea derivatives with very good yield under mild reaction conditions
The transition-metalcatalyzed synthesis of 1,2,4-triazoles from readily available starting materials were reported with low yield and harsh conditions [5]
Summary
Substituted 1,2,4-triazole and its derivatives have gained a considerable interest of the medicinal chemist in search for the new drugs. Abstract: We reported here the microwave assisted synthesis of 3,5-disubstituted 1,2,4-triazole based piperazine amide and urea derivatives with very good yield under mild reaction conditions.
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