Abstract

Ten novel methyl 3α-(4-nitrobenzoylhydrazides)-12 α-( L-amino acid carbamates)-cholan-24-oate chiral molecular tweezers based on deoxycholic acid have been easily constructed using microwave irradiation. Their structures were characterised by IR, 1H NMR, MS spectra and elemental analysis and their molecular recognition properties were investigated by UV-Vis spectral titration. The preliminary study indicated that these target compounds possess good selectivity for D/L amino acid methyl esters.

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