Microwave Assisted Synthesis and Characterization of Silver Nanoparticles using Tridax procumbens and its Anti-Inflammatory Activity against Human Blood Cells

Abstract

Microwave Assisted Synthesis and Characterization of Silver Nanoparticles using Tridax procumbens and its Anti-Inflammatory Activity against Human Blood Cells Nature has been a source of medicinal agents for thousands of years and an impressive number of modern drugs have been isolated from natural resources. Traditional medicine is an important source of potentially useful new compounds for the development. The plant extract is mixed with AgNO3 and incubated. The synthesised silver nanoparticle was confirmed by colour transformation. It was characterized by UV–Vis spectroscopy, FTIR, XRD & TEM. In general, the sizes of nanoparticles were found to be 1-100nm. The results showed that the leaf extract is optimum for the synthesis of silver nanoparticles and it is also known to have the ability to inhibit the growth of various pathogenic microorganisms. The size of synthesized silver nanoparticles is found to be 35.84 nm using XRD data by Scherrer’s formula, which is approximately similar as the size obtained in TEM analysis (35.71 nm). In totality, the AgNPs prepared are safe to be discharged in the environment and possibly utilized in processes of pollution remediation. AgNPs may also be efficiently employed in Anti-inflammatory activity of Pharmaceutical research to obtain better result of plant as shown by our study. The anti-inflammatory activity of silver nanoparticles was tested and confirmed against human blood cells. Hence, the present research aims to open new avenues for the improvement of medicinal uses with the synthesis of silver nanoparticles by using Tridax procumbens extract for various ailments and to bring the anti-inflammatory medicinal plant to the scientist’s notice, to educate awareness and add values to the resource.