Abstract
An efficient one-pot synthesis of 6-carbethoxy-5-aryl-3-(2-thienyl)-2-cyclohexenones (4a-g) has been achieved by the cyclocondensation of (2E)-1-(2-thienyl)-3-aryl-2-propenones (1) with ethyl acetoacetate (EAA) under microwave irradiation (MWI) using inorganic solid support. The synthesis highlights a comparative study of microwave and conventional techniques and catalytic role of various inorganic support used. All the products have been characterized by IR, 1 H NMR and MS study and screened for their antibactcrial activity.
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