Abstract
AbstractAn expeditious catalyst‐free heteroannulation has been accomplished to access functionalized thiazol‐2(3H)‐ones by the reaction of isothiocyanates and 2‐bromoketones in EtOH under controlled microwave irradiation heating. The synthetic strategy is simple, straightforward, and offers two points of structural diversity to expand the product versatility. Further, the biological relevance of the synthesized thiazol‐2(3H)‐ones has been examined for their possible use as putative acetylcholinesterase inhibitors through molecular docking analysis.
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