Microwave-assisted asymmetric ring opening of meso-epoxides with aromatic amines catalyzed by a Ti- S-(−)-BINOL complex

Rukhsana I Kureshy,Surendra Singh,Noor-Ul H Khan,Sayed H.R Abdi,Santosh Agrawal,Vishal J Mayani,Raksh V Jasra

doi:10.1016/j.tetlet.2006.05.150

Microwave-assisted asymmetric ring opening of meso-epoxides with aromatic amines catalyzed by a Ti- S-(−)-BINOL complex

Rukhsana I Kureshy, Surendra Singh + Show 5 more

https://doi.org/10.1016/j.tetlet.2006.05.150

Copy DOI

Journal: Tetrahedron Letters	Publication Date: Jun 13, 2006
Citations: 39

Affiliation: Central Salt and Marine Chemicals Research Institute

#Ring Opening Of Cyclohexene Oxide #Asymmetric Ring Opening Of Meso-epoxides + Show 8 more

Abstract
Full-Text PDF
Similar Papers

Abstract

Catalytic asymmetric ring opening of cyclohexene oxide and meso-stilbene oxide with anilines was catalyzed by a Ti-( S)-(−)-BINOL complex to afford β-amino alcohols in high yield (up to 95%) and good enantioselectivities (ee up to 55%) under microwave irradiation. The reaction using a microwave was found to be 10 times faster than traditional oil-bath heating with retention of enantioselectivity.

Full Text