Abstract
Detection of microvascular obstruction (MO) with gadolinium first-pass perfusion (FP) and late gadolinium enhancement (LGE) MRI predicts outcomes of STEMI patients. Previous data indicate the presence of MO early after MI correlates to worse prognosis and left ventricular (LV) remodeling. Nonetheless, FP and early hypoenhancement on LGE may persist after reperfused STEMI for a variable period of time.
Highlights
Detection of microvascular obstruction (MO) with gadolinium first-pass perfusion (FP) and late gadolinium enhancement (LGE) MRI predicts outcomes of STEMI patients
We investigate whether the persistence of MO by CMR was related to worse left ventricular (LV) remodeling at 6 month after STEMI
LV ejection fraction at six month was significantly lower in persistent MO group compared to transient and absent MO (43.6±9.7% vs 47.1±7.9% vs 62.5 ±15.7%, p=0.006 by ANOVA, p
Summary
Detection of microvascular obstruction (MO) with gadolinium first-pass perfusion (FP) and late gadolinium enhancement (LGE) MRI predicts outcomes of STEMI patients. Previous data indicate the presence of MO early after MI correlates to worse prognosis and left ventricular (LV) remodeling. FP and early hypoenhancement on LGE may persist after reperfused STEMI for a variable period of time. Purpose We investigate whether the persistence of MO by CMR was related to worse LV remodeling at 6 month after STEMI
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