Abstract

Diaspirin crosslinked hemoglobin (DCLHb™, Baxter Healthcare Corp) is a hemoglobin based blood substitute which has been demonstrated to restore systemic blood pressure following hypovolemic shock at a low dose in pigs. In this study microvascular pO2 of the pig gut (pO2microv) was measured with a light guide attached to a phosphorimeter and using Pd-porphyrin quenching of phosphorescence [1], during shock and resuscitation. Resuscitation with DCLHb™ was compared to resuscitation with a combination of crystalloid and colloid.

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