Abstract

Objective To investigate the clinical effect of microvascular decompression for patients with cranial nerve disease complicated with hypertension. Methods A total of 287 patients with cranial nerve disease complicated with hypertension were enrolled in our hospital from February, 2012 to January, 2017, and were divided into a conventional group and an improved group according to the admission time. The conventional group (135 cases) underwent conventional microvascular decompression (MVD), and the improved group (152 cases) improved MVD surgery (improvement in posture, decompression implant, decompression method, cranial method, and neuroelectrophysiological monitoring). The patients were followed up for 10 to 32 months. The curative effect, blood pressure before operation and 1 week and 10 months after operation, and complication rate in the two groups were observed. Results The total effective rate was higher and the postoperative complication rate was lower in the improved group than in the conventional (98.68% vs. 93.33% and 2.63% vs. 9.63%, both P 0.05). The systolic blood pressure and diastolic blood pressure of the two groups were lower after than before the operation in both groups, and were lower in the improved group than in the conventional group, with statistical differences (P<0.05). Conclusion Microvascular decompression for cranial nerve disease complicated with hypertension is safe and effective; and the improved operation is more conducive in improving blood pressure and clinical efficacy as well as reducing complications. Key words: Cranial neuropathy; Hypertension; Microvascular decompression; Clinical efficacy

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