Abstract
SummaryAn improved formula for a cacodylate-buffered glutaraldehyde and osmium tetroxide fixative which contains sucrose and magnesium sulfate is described; it provides excellent preservation and visualization of cytoplasmic microtubules in cells of the anterior pituitary gland. The extensive distribution of microtubules in prolactin cells of the rats killed during lactation is illustrated. They occur in close association with mitochondria, secretory granules, endoplasmic reticulum, Golgi lamellae, nuclear envelopes and plasma membranes. Although marked alterations in the number or distribution of the microtubules were not seen in relation to alterations in prolactin secretion, it is suggested that quantitative morphometric procedures may be necessary for a reliable evaluation of changes in microtubules.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
