Abstract
Abstract Intracellular motility in eukaryotic cells is generated by motor proteins, which drive directional transport along cytoskeletal filaments such as microtubules, the primary intracellular rail system. These cytoplasmic cytoskeletal elements provide not only structure and support to the cell but also an intracellular directional railway that allows components of the cell to be transported outside of organelles (Hirokawa and Takemura, 2005). This railway system transports molecular complexes and organelles after synthesis in the cell body to their proper peripheral location. Similarly, endocytic vesicles are transported from the cell surface to the center of the cell. In the cell, microtubule plus ends are directed toward the cell membrane and minus ends are anchored at the centrosome, one type of the microtubule-organizing center (MTOC) in a cell.
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