Abstract
Microstimulation of the intermediate layers of V1 in rhesus monkeys disrupts target selection with saccadic eye movements. To study target selection, one visual target was presented in the receptive-field location of the stimulated neurons and a second target was presented outside this location. Microstimulation delivered with the appearance of the two targets decreased the probability that the monkey would select the target placed in the receptive-field location when intermediate layers of V1 were stimulated. This interference effect was more pronounced when anodal-first pulse pairs were used as compared to when cathodal-first pulse pairs were used. The superior effectiveness of anodal pulses suggests that the interference effect is due to activation of axonal terminals residing within intermediate V1.
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