Abstract
Conventional dosage forms provide a sharp increase in plasma drug levels that falls below the therapeutic range after short interval of time until the re-administration of drug. There is a need of such dosage forms which provide not only sustained drug delivery but also reduce the plasma drug levels fluctuations. Microspheres used in drug delivery systems due to their ability to sustain the drug release, their biodegradability and compatibility and targeted drug delivery. In this review different types of microspheres their methods for the preparation with different hydrophilic and hydrophobic polymers, drug loading capacities will be discussed. Different characterizations like SEM, FTIR, XRD, DSC, rheological properties and invitro drug release are successfully described.
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