Abstract
MICE bearing the X-linked testicular feminisation (Tfm)1 gene in the hemizygous (X/Y) state have been presumed to have no traces of the male genital system. Unlike normal genetic males2, they are apparently unresponsive to the androgens produced by the developing testes3,4, and it has been presumed that derivatives of the embryonic mesonephric (Wolffian) duct system (MDS) are unable to survive in Tfm/Y males. I describe here, however, microscopic components of the complex comprising rete testis, efferent ductules, epididymis and, sometimes, vas deferens in adult Tfm/Y mice. These structures are unrelated to the effects of the presumed mutation Ohv, to which the microscopic epididymides of some Tfm/Y mice have been ascribed5.
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