Abstract
Introduction: Ampulla of Vater cancer(AoVca) is one of the periampullary cancers with a better prognosis, but recurrence still occurs early in some patients. The aim of this study was to evaluate risk factors of early recurrence after curative resection of AoVca. Method: Between January 2005 and December 2012, 123 patients received radical resection for AoVca at Yonsei University Medical Center. 74 patients with T1 or 2 stage AoVca were reviewed and analyzed to assess risk factor of early recurrence. Result: Among the 74 patients, nineteen patients (25.7%) experienced recurrent disease. Thirteen patients (17.5%) suffered recurrent disease within 12 months (early recurrence). The median follow-up for non-recurrence was 81.3 months, 17.6 months for early recurrence, and 34.4 months for late recurrence. After Multiivariate analysis, lymph node involvement(odds ratio 4.34, P=0.02), microsatellite instability (odds ratio; 8.01, P<0.01) were significant predictors for early recurrence. Conclusion: Lymph node involvement and microsatellite instability were found to be predictors for early recurrence.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
