Abstract
We recently reported an interesting finding that the Ebola virus (EBOV) encodes functional microRNAs (miRNAs) that can be produced through the cellular miRNA processing machinery. In addition, the prediction of EBOV miRNA target genes provided some clues about the regulatory roles of EBOV miRNAs. In summary, our findings provide a basis for further assessing the roles of the EBOV miRNAs in viral infection and virus-host interactions.
Highlights
MicroRNAs are a class of small non-coding RNAs that play pivotal roles in a variety of physiological processes [4, 5]. miRNAs are found in eukaryotes but are transcribed by various viruses to manipulate their own genes and/or the hosts’ genes [6, 7], and they are believed to be important regulators of the virus-host interaction and key elements in viral pathogenesis [8]
We recently reported an interesting finding that the Ebola virus (EBOV) encodes functional microRNAs that can be produced through the host’s miRNA processing machinery
Our study paves the road for further investigating the roles of EBOV miRNAs in viral infection and virus-host interactions
Summary
MicroRNAs (miRNAs) are a class of small non-coding RNAs that play pivotal roles in a variety of physiological processes [4, 5]. miRNAs are found in eukaryotes but are transcribed by various viruses to manipulate their own genes and/or the hosts’ genes [6, 7], and they are believed to be important regulators of the virus-host interaction and key elements in viral pathogenesis [8]. We recently reported an interesting finding that the Ebola virus (EBOV) encodes functional microRNAs (miRNAs) that can be produced through the host’s miRNA processing machinery. Prediction of EBOV miRNA target genes provided some clues about the regulatory roles of EBOV miRNAs. In summary, our study paves the road for further investigating the roles of EBOV miRNAs in viral infection and virus-host interactions.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
