Abstract
Interstitial fluid pressure (IFP) in normal and inflamed gingiva of rats was measured by sharpened glass capillaries (diameter 2-4 microns) connected to a servocontrolled counterpressure system ad modum Wiederhielm. Gingival inflammation was induced by a steel ligature placed unilaterally around the first maxillary molar. After 8 weeks, the ligature was removed and measurements of IFP in normal and experimentally inflamed gingiva were made by puncture through the intact oral epithelium. Average IFP on the control side was 3.5 mm Hg in free, and 7.4 mm Hg in attached gingiva. Compared to the control side, IFP on the experimental inflamed side was elevated significantly (p less than 0.05) both in free and attached gingiva. In the ligated inflamed side IFP in free gingiva averaged 6.7 mm Hg, whereas in attached gingiva it showed a mean value of 10.4 mm Hg. Histological examinations showed a dense infiltrate of inflammatory cells in the connective tissue, while the contralateral control side showed normal features of epithelial and connective tissue. The present finding of increased IFP in the inflamed gingiva may in theory contribute to augmented crevicular fluid flow during inflammation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
