Microperimetry-Assessed Functional Alterations and OCT-Changes in Patients after Retinal Detachment Surgery Using Pars Plana Vitrectomy and SF6 Tamponade.

María D Díaz-Barreda,Ana Boned-Murillo,Isabel Pinilla,Elvira Orduna-Hospital,Isabel Bartolomé-Sesé,Francisco J Ascaso,Antonio Ferreras

doi:10.3390/diagnostics11071157

Abstract

Background: We study the retinal function measured by macular integrity assessment microperimetry (MAIA) and structural changes assessed by scanning swept source optical coherence tomography (SS-OCT) between healthy individuals and patients undergoing pars plana vitrectomy (PPV) after rhegmatogenous retinal detachment (RRD). Methods: Cross-sectional study. Early Treatment Diabetic Retinopathy Study (ETDRS) grids were measured by SS-OCT and compared with the MAIA parameters. Results: Thirty-eight eyes with RRD (19 macula-on and 19 macula-off) were compared with 113 healthy eyes. The retinal sensitivity and average total threshold were reduced in all sectors in the RRD group; macular integrity index was increased. Macular thicknesses in total retina and ganglion cell layer (GCL)++ protocols were higher in the RRD group in nasal outer (NO) and central (C) sectors and only in C sector for GCL+ protocol. Thicknesses were lower in total retina, GCL++ protocols in the temporal outer (TO) sector and in the GCL+ protocol in NO sector. Best-corrected visual acuity (BCVA) correlated moderately with retinal sensitivity in all sectors and in just several sectors with time between the date of surgery and the test. The central nasal (CN) sector thickness and the average total threshold were higher in the macula-on subgroup. Conclusions: RRD and subsequent surgery results in functional and structural changes, especially in individuals with macular detachment.

Highlights

Rhegmatogenous retinal detachment (RRD) is the most common type of retinal detachment with an incidence between 9.5 and 18.2 cases per 100,000 inhabitants per year [1]
The aim of the present study was to evaluate and compare the retinal thickness changes measured by swept source optical coherence tomography (SS-OCT) and the functional parameters obtained with macular integrity assessment (MAIA) microperimetry between eyes that underwent rhegmatogenous retinal detachment (RRD) surgery depending on the previous macula status and healthy eyes
We studied a consecutive series of RRD treated with 23G pars plana vitrectomy (PPV), endophotocoagulation and 25% SF6 as tamponade

Summary

Introduction

Rhegmatogenous retinal detachment (RRD) is the most common type of retinal detachment with an incidence between 9.5 and 18.2 cases per 100,000 inhabitants per year [1]. The importance of macular involvement is not well-known for the end retinal sensitivity result [7] Presurgical variables, such as previous best-corrected VA (BCVA); time between the onset of symptoms and surgery; extension of the RRD; macular involvement before surgery; vitreomacular traction and distance between the outer limiting membrane and photoreceptors outer segments measured by optical coherence tomography (OCT) may affect the final best-corrected visual acuity (BCVA) and other functional parameters [4,5,8]. We study the retinal function measured by macular integrity assessment microperimetry (MAIA) and structural changes assessed by scanning swept source optical coherence tomography (SS-OCT) between healthy individuals and patients undergoing pars plana vitrectomy (PPV) after rhegmatogenous retinal detachment (RRD). Conclusions: RRD and subsequent surgery results in functional and structural changes, especially in individuals with macular detachment

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