Abstract
Articles of Russian and foreign authors for the period from 2000 until 2012 devoted to the problems of use, analysis, and interpretation of the results of micronucleus test of human buccal epithelium were analyzed. Nuclear anomalies, detected in the cells of the oral cavity mucous membrane, were described. The studies, devoted to analysis of the influence of the method of micronucleus test conduction (coloration, scrape capture) on its results, were summarized. Modern ideas about the factors of different etiology that induce the origin of nucleus aberrations (sex, age, genotype, psychophysiological characteristics, immune status, diseases of different etiology, anthropogenic pollution of the environment, climatic and geographical conditions, ionizing and nonionizing radiations, chemical compounds (medical preparations, biologically active additives, androgenic steroids, et al.), dental fillings, occupational hazards, alcoholism, use of tobacco mixtures) were summarized as a scheme. Problems and unresolved issues associated with peculiarities of micronucleus test usage were emphasized.
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