Abstract
The present article is concerned with the study of glial fibrillary acidic protein (GFAP) level in the blood serum of pregnant women with post–trauma brain injury syndrome (post-TBI syndrome) as the marker of hematoencephalic barrier status and predictor of obstetric and perinatal complications development.
Highlights
It is known that central nervous system plays the most important role in maintenance and normal functioning of all systems and organs in humans organism, including pregnancy. Cipolla et al (2011) writes diseases of central nervous system can be the reason of many maternal and fetal complications during pregnancy period
Algattas et al (2014) writes posttrauma brain injury syndrome or post coma syndrome develops after brain trauma, which nowadays takes 50% of all traumas
Astrocytes and endotheliocytes are in close relationship one to each other astrocytes produce substances, which influence on permeability of hematoencephalic barrier (Yang et al, 2013)
Summary
It is known that central nervous system plays the most important role in maintenance and normal functioning of all systems and organs in humans organism, including pregnancy. Cipolla et al (2011) writes diseases of central nervous system can be the reason of many maternal and fetal complications during pregnancy period. With the growth of brain traumas, connected with car accidents, there is a progressive growth of female drivers and as a result increased frequency of occurrence of postTBI syndrome in women (Paul et al, 2013). Such a progression is mostly connected with a dysfunction in permeability of hematoencephalic barrier and exhaustion of compensatory mechanisms, which maintain normal function of pregnant organism (Gao et al, 2011).
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