Abstract
Melasma is a hormone-related and ultraviolet radiation-activated form of hyperpigmentation that appears as bilateral facial macules. It is often claimed to be the most challenging type of hyperpigmentation to treat, as there is a high risk of the condition becoming worse. As melanocytes are highly sensitive to heat and collateral damage created by keratinocyte thermolysis, microneedling delivers innovative and effective results, while respecting melanocyte integrity. A corrective cascade is activated by the release of regulatory growth factors for quick and impressive outcomes. Treatment with microneedling is suitable for all Fitzpatrick skin types and heritages. Combination therapies with microneedling, including the infusion of active depigmenting agents, deliver even greater treatment versatility and results. Patient commitment to the daily topical application of both pigment-blockers and a high sun protection factor enable further long-term management of this chronic, recalcitrant skin condition.
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