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Abstract
Background: Controversy surrounds the management of micro-metastases within sentinel lymph node biopsy (SNB). Current NICE guidance is to offer axillary lymph node clearance (ANC) following micrometastases on SNB based on evidence from two systematic reviews. This is likely to be debated following publication of ACOSOG Z0011 and the imminent publication of IBCSG 23-01. Both studies showed no benefit in overall, disease free survival or axillary recurrence rates of ANC over SNB alone.
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