Abstract
BackgroundInternational guidelines on the prevention of caries recommend sealing of the pits and fissures of the permanent molars. There is no evidence on which type of material is most effective on demineralized enamel.AimTo evaluate the microleakage of a conventional light-cured, resin-based fissure sealant (LCRBS), GrandiO Seal, and a resin-modified glass ionomer sealant (RMGIS), Vitremer, after application of a fluoride varnish, Bifluorid 12, on demineralized enamel.Design80 human third molars were divided into eight groups. The groups combined the three study factors (1) type of enamel (intact or demineralized); (2) enamel non-varnished or varnished with Biflourid12; and (3) type of sealant (GrandiO Seal or Vitremer). The percentage of microleakage after thermocycling was measured using imaging analysis software. The Kruskal-Wallis plus Dunn tests were used to compare differences in microleakage in the different groups.ResultsThe lowest microleakage was in the unvarnished groups, and was the same for GrandiO Seal and Vitremer. When varnish was applied, microleakage was greater in demineralized enamel than in intact enamel for both LCRBS and RMGIS.ConclusionThe application of fluoride varnish on demineralized enamel increases the microleakage of both GrandiO Seal and Vitremer.
Highlights
IntroductionThe Global Burden of Disease (GBD) 2015 study [1] found that untreated caries in the permanent teeth was the most highly-prevalent condition measured, (age-standardized prevalence: 34.1%), affecting 2.5 billion people worldwide (95% UI: 2.4 to 2.7 billion)
The Global Burden of Disease (GBD) 2015 study [1] found that untreated caries in the permanent teeth was the most highly-prevalent condition measured, affecting 2.5 billion people worldwide (95% UI: 2.4 to 2.7 billion)
Microleakage was greater in demineralized enamel than in intact enamel for both LCRBS and resin-modified glass ionomer sealant (RMGIS)
Summary
The Global Burden of Disease (GBD) 2015 study [1] found that untreated caries in the permanent teeth was the most highly-prevalent condition measured, (age-standardized prevalence: 34.1%), affecting 2.5 billion people worldwide (95% UI: 2.4 to 2.7 billion). The greatest risk of caries lesions in permanent teeth occurs during the first years after eruption, due to the lack of posteruptive maturation of the enamel [3] and they most frequently appear on the pits and fissures of the first molars, where they appear even before eruption is complete, because the anatomy favours the formation and retention of biofilm [4]. International dentistry and paediatric dentistry guidelines recommend sealing the primary and permanent molars in children and adolescents to prevent the onset of cavities and minimize the progression of noncavitated occlusal carious lesions [5,6]. International guidelines on the prevention of caries recommend sealing of the pits and fissures of the permanent molars. There is no evidence on which type of material is most effective on demineralized enamel
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