Abstract
M.S.S. is a 54-year-old white female patient with main complaint: For more than 2 years appeared a small white spot on the tongue that had been increased. The anamnesis revealed no history of alcohol and tobacco consumption and diabetes and hypertension controlled with medication and diet. The patient reported previous biopsy 2 months ago, whose histopathologic diagnosis was leukoplakia with mild epithelial dysplasia. Intraoral clinical examination detected a leukoplastic lesion with a granular surface located on the right border of the tongue. After toluidine blue test, an incisional biopsy was performed in the positive area, and the surgical specimen was submitted for anatomopathologic analysis. The histopathologic diagnosis was microinvasive squamous cell carcinoma, and the patient was referred to the regulation system. This report demonstrates the importance of biopsy and toluidine blue test on investigation of white lesions for the early diagnosis of oral squamous cell carcinoma.
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