Abstract

Objective To explore the feasibility and optimal operating methods of microinvasional surgery for the occupying lesions at sella region in matrical hospital. Methods to analyse 70 cases with lesion at sella region from 2003 to 2009, including 56 patients with pituitary adenoma, 1 with metastatic carcinoma, 3 with craniopharyngioma, 2 with meningioma, 1 with chordoblastoma, 3 with empty sella syndrome, 2 with cerebrospinal rhinorrhea, 2 with optic nerve decompression. Twenty-nine patients were managed by micro transnasal-sphenoidal approach, 15 by combined application of nasal endoscope and microscope, 26 by nasal endoscope. Results Of all 56 patients with pituitary adenoma, the tumors were totally removed in 27 cases and subtotally removed in 24 cases, partial removed in 5 cases. The tumor of the patient with metastatic carcinoma was subtotally removed, totally removed in 2 cases with meningioma, subtotally removed in 1 case with chordoblastoma. Of all 3 patients with empty sella syndrome, eyesight was evidently improved in 2 cases, no changed in one. Neoplasty was done well in 2 cases with cerebrospinal rhinorrhea. Optic nerve decompression has a good effect in one, ineffective in one cases. Conclusions Microinvasional surgical therapy can get breakthrough through the alliance of clinical divisions and the share of facilities in matrical hospital. The optimal operating method is the transnasal-sphenoidal approach by nasal endoscope, but it can not replace microsurgical intervention. We should utilize respective advantages in the treatment for the occupying lesions at sella region. Key words: Matrical hospital ; Sella region ; Microinvasional surgery ;

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