Abstract

Microincision of the cystic duct and its confluence part, which facilitated the application of transcystic-laparoscopic common bile duct (CBD) exploration (transcystic-LCBDE), had been described in some reports. However, it is unclear whether transcystic-LCBDE with microincision (micro-LCBDE) is effective and safe as transductal-LCBDE for the failed transcystic-LCBDE in patients with choledocholithiasis. In this retrospective cohort study, we assigned patients with cholecystocholedocholithiasis to undergo transcystic-LCBDE and laparoscopic cholecystectomy. The clinical outcomes of one-to-one propensity-matched pairs of Micro-LCBDE and transductal-LCBDE groups were compared. Between January 2007 and December 2018, 1650 patients with confirmed choledocholithiasis attempted transcystic-LCBDE. Micro-LCBDE was done successfully in 128 patients (7.8%) and transductal-LCBDE in 69 patients (4.2%). By one-to-one propensity score matching, 68 pairs were selected. There was no significant difference in in-hospital complication rate: 8.8% in micro-LCBDE group and 11.8% in transductal-LCBDE group (p = 0.573). The duration of operation in micro-LCBDE was a little shorter than that in transductal-LCBDE: median 125 (interquartile range 95-173) versus 150 (120-195) min respectively (p = 0.003). Postoperative recovery was faster in micro-LCBDE than in transductal-LCBDE, as reflected by a shorter postoperative hospital stay (median 3 versus 5 days, p = 0.002, respectively). There was also no significant difference in rates of retained stone and recurrence of CBD stone between the groups. Our findings suggest that micro-LCBDE surgery was effective and safe as transductal-LCBDE surgery in patients with failed transcystic-LCBDE, suggesting that the micro-LCBDE is an acceptable alternative to transductal-LCBDE for failed transcystic-LCBDE.

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