Abstract
The recent advances (e.g. combinatorial chemistry and high-throughput screening) in the discovery of drug candidates that can potentially treat various diseases have pushed the pharmaceutical industry through a period of unparalleled changes in drug development. However, the process to identify, filter and test a potential drug candidate can still be laborious and time-consuming. The drug candidate is passed through different stages of development, i.e. target selection (e.g. gene or protein), molecule identification and preclinical studies (in vitro and in vivo tests), which are then followed by clinical trials and manufacturing. It is, therefore, of paramount importance to develop improved high-throughput technologies that can significantly reduce the time and cost consumption while meeting the strict guidelines for good manufacturing practice (GMP). One such innovative technology that can supplement existing practices and enable the pharmaceutical industry to achieve a paradigm shift in drug development and operational manufacturing is microfluidics. In this chapter, we will review the applications of microfluidics in the drug discovery and development process.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
