Abstract
In recent years, the potential clinical value of circulating tumor cells (CTCs) is more obvious, and a myriad of detection methods for CTCs have been developed. Among them, a series of microfluidic devices are particularly promising as they uniquely offer micro-scale analytical systems that are highlighted by low consumption of samples and reagents, high flexibility to accommodate other cutting-edge technologies, precise and well-defined flow behaviors, and automation capability, presenting themselves significant advantages over the conventional larger systems. Here, a brief review of the recent advances in the CTC detection by microfluidic devices and their challenges in clinical application will be given.(Chin J Lab Med, 2018, 41: 638-640) Key words: Neoplastic cells, circulating; Microfluidics; Cell separation; Nanotechnology
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