Abstract

One of the major topics of research in modern cell biology involves the structure and organization of the cytoskeleton and, in particular, the interaction of its various components with the plasma membrane. Studies carried out in many laboratories over the last several years pointed to the complex and heterogeneous nature of membrane-cytoskeleton interactions in different systems. This is manifested by a remarkable cell-type specificity as well as distinct differences between the mode of anchorage of the various cytoskeletal components. Moreover the assembly and maintenance of each of the cytoskeletal systems within individual cells appears to be a dynamic process which is probably spatially and temporally regulated and modulated.

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