Abstract
AbstractChemical analyses of brain interstitial fluid can reveal important information about local brain metabolism and neurochemistry, and can enhance our understanding of how neuronal networks respond to physiological or pathological stimuli. Among brain monitoring methods currently available, microelectrode biosensors provide real‐time analyses with high temporal resolution and minimal perturbation to living tissue by using oxidase enzymes for biological recognition. Two types of microelectrodes are used: cylindrically shaped wire electrodes provide the smallest implantable devices to date, and microfabricated multi‐electrode needles can monitor several molecules simultaneously. They have already contributed significantly to our understanding of brain energy metabolism with glucose and lactate detection, and to neurotransmitter systems with glutamate, D‐serine, acetylcholine, and purine detection. They have the potential to undergo further technological developments in future studies.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.