Abstract
Objective: One of the most difficult challenges in assisted reproduction is the management of patients who respond poorly to gonadotrophin stimulation. Among a variety of strategies aimed at improving response is the follicular phase administration of microdoses of GnRH-a (Fertil.Steril, 1998; 69:419–424). However, it has been suggested that the beneficial effects of this protocol may result from the concomitant use of the oral contraceptive pill (Fertil.Steril, 1999; 72:1018–1023). The objective of this study was to compare the response and outcomes of microdose GnRH-a flare protocol with a standard dose long GnRH-a protocol utilizing the oral contraceptive pill in age matched patients undergoing in vitro fertilization.
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