Abstract

Microcystic/Reticular Schwannoma [MRS] is a rare histological variant of Schwannoma which has been reported to mainly affect the gastrointestinal tract. Few cases involving soft tissue and various visceral and salivary glands have also been reported. However, MRS involving the spine is extremely rare with only two cases reported till date. Hereby, we present a case of Microcystic/Reticular schwannoma in a middle aged female who presented with complaints of pain and numbness in both legs. MRI findings were suggestive of an intradural extramedullary neoplasm. Diagnosis of MRS was made based on the typical histopathological features and Immunohistochemical positivity for S100. MRS is a variant of Schwannoma, which differs from the conventional Schwannoma in several aspects. Raising awareness regarding this variant is essential to the budding pathologists to prevent their misdiagnosis. Keywords: Nerve sheath tumors, Benign neural neoplasms, Myxoid neural masses, Spinal schwannomas.

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